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On the analysis of clonogenic survival data: Statistical alternatives to the linear-quadratic model

BACKGROUND: The most frequently used method to quantitatively describe the response to ionizing irradiation in terms of clonogenic survival is the linear-quadratic (LQ) model. In the LQ model, the logarithm of the surviving fraction is regressed linearly on the radiation dose by means of a second-de...

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Detalles Bibliográficos
Autores principales: Unkel, Steffen, Belka, Claus, Lauber, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730743/
https://www.ncbi.nlm.nih.gov/pubmed/26822015
http://dx.doi.org/10.1186/s13014-016-0584-z