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Targeting NF-κB in glioblastoma: A therapeutic approach

Glioblastoma multiforme (GBM) is the most common and lethal form of intracranial tumor. We have established a lentivirus-induced mouse model of malignant gliomas, which faithfully captures the pathophysiology and molecular signature of mesenchymal human GBM. RNA-Seq analysis of these tumors revealed...

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Detalles Bibliográficos
Autores principales: Friedmann-Morvinski, Dinorah, Narasimamurthy, Rajesh, Xia, Yifeng, Myskiw, Chad, Soda, Yasushi, Verma, Inder M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730860/
https://www.ncbi.nlm.nih.gov/pubmed/26824076
http://dx.doi.org/10.1126/sciadv.1501292