Iridium-Catalyzed Reductive Nitro-Mannich Cyclization

A new chemoselective reductive nitro-Mannich cyclization reaction sequence of nitroalkyl-tethered lactams has been developed. Relying on the rapid and chemoselective iridium(I)-catalyzed reduction of lactams to the corresponding enamine, subsequent nitro-Mannich cyclization of tethered nitroalkyl fu...

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Detalles Bibliográficos
Autores principales: Gregory, Alex W, Chambers, Alan, Hawkins, Alison, Jakubec, Pavol, Dixon, Darren J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730865/
https://www.ncbi.nlm.nih.gov/pubmed/25399919
http://dx.doi.org/10.1002/chem.201405256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730865/
https://www.ncbi.nlm.nih.gov/pubmed/25399919
http://dx.doi.org/10.1002/chem.201405256

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