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Iridium-Catalyzed Reductive Nitro-Mannich Cyclization

A new chemoselective reductive nitro-Mannich cyclization reaction sequence of nitroalkyl-tethered lactams has been developed. Relying on the rapid and chemoselective iridium(I)-catalyzed reduction of lactams to the corresponding enamine, subsequent nitro-Mannich cyclization of tethered nitroalkyl fu...

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Detalles Bibliográficos
Autores principales:	Gregory, Alex W, Chambers, Alan, Hawkins, Alison, Jakubec, Pavol, Dixon, Darren J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2015
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730865/ https://www.ncbi.nlm.nih.gov/pubmed/25399919 http://dx.doi.org/10.1002/chem.201405256

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