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Super-resolution microscopy reveals altered desmosomal protein organization in pemphigus vulgaris patient tissue

Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease in which autoantibodies (IgG) are directed against the desmosomal cadherin desmoglein 3 (Dsg3). In order to better understand how PV IgG alters desmosome morphology and function in vivo, PV patient biopsies were analyzed by struct...

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Detalles Bibliográficos
Autores principales: Stahley, Sara N., Warren, Maxine F., Feldman, Ron J., Swerlick, Robert A., Mattheyses, Alexa L., Kowalczyk, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730957/
https://www.ncbi.nlm.nih.gov/pubmed/26763424
http://dx.doi.org/10.1038/JID.2015.353