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Super-resolution microscopy reveals altered desmosomal protein organization in pemphigus vulgaris patient tissue
Pemphigus vulgaris (PV) is an autoimmune epidermal blistering disease in which autoantibodies (IgG) are directed against the desmosomal cadherin desmoglein 3 (Dsg3). In order to better understand how PV IgG alters desmosome morphology and function in vivo, PV patient biopsies were analyzed by struct...
Autores principales: | Stahley, Sara N., Warren, Maxine F., Feldman, Ron J., Swerlick, Robert A., Mattheyses, Alexa L., Kowalczyk, Andrew P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730957/ https://www.ncbi.nlm.nih.gov/pubmed/26763424 http://dx.doi.org/10.1038/JID.2015.353 |
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