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Multivariate Calibration Approach for Quantitative Determination of Cell-Line Cross Contamination by Intact Cell Mass Spectrometry and Artificial Neural Networks

Cross-contamination of eukaryotic cell lines used in biomedical research represents a highly relevant problem. Analysis of repetitive DNA sequences, such as Short Tandem Repeats (STR), or Simple Sequence Repeats (SSR), is a widely accepted, simple, and commercially available technique to authenticat...

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Detalles Bibliográficos
Autores principales: Valletta, Elisa, Kučera, Lukáš, Prokeš, Lubomír, Amato, Filippo, Pivetta, Tiziana, Hampl, Aleš, Havel, Josef, Vaňhara, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731057/
https://www.ncbi.nlm.nih.gov/pubmed/26821236
http://dx.doi.org/10.1371/journal.pone.0147414