LDLR and PCSK9 Are Associated with the Presence of Antiphospholipid Antibodies and the Development of Thrombosis in aPLA Carriers

INTRODUCTION: The identification of the genetic risk factors that could discriminate non- thrombotic from thrombotic antiphospholipid antibodies (aPLA) carriers will improve prognosis of these patients. Several human studies have shown the presence of aPLAs associated with atherosclerotic plaque, wh...

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Detalles Bibliográficos
Autores principales: Ochoa, Eguzkine, Iriondo, Mikel, Manzano, Carmen, Fullaondo, Asier, Villar, Irama, Ruiz-Irastorza, Guillermo, Zubiaga, Ana M., Estonba, Andone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731066/
https://www.ncbi.nlm.nih.gov/pubmed/26820623
http://dx.doi.org/10.1371/journal.pone.0146990