Differential Toxicity of Antibodies to the Prion Protein

Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...

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Detalles Bibliográficos
Autores principales: Reimann, Regina R., Sonati, Tiziana, Hornemann, Simone, Herrmann, Uli S., Arand, Michael, Hawke, Simon, Aguzzi, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://www.ncbi.nlm.nih.gov/pubmed/26821311
http://dx.doi.org/10.1371/journal.ppat.1005401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731068/
https://www.ncbi.nlm.nih.gov/pubmed/26821311
http://dx.doi.org/10.1371/journal.ppat.1005401

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