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Differential Toxicity of Antibodies to the Prion Protein
Antibodies against the prion protein PrP(C) can antagonize prion replication and neuroinvasion, and therefore hold promise as possible therapeutics against prion diseases. However, the safety profile of such antibodies is controversial. It was originally reported that the monoclonal antibody D13 exh...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731068/ https://www.ncbi.nlm.nih.gov/pubmed/26821311 http://dx.doi.org/10.1371/journal.ppat.1005401 |