Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats

BACKGROUND AND AIMS: By blocking TNFα-related effects, thalidomide not only inhibits hepatic fibrogenesis but improves peripheral vasodilatation and portal hypertension in cirrhotic rats. Nonetheless, the investigation of thalidomide's effects on splanchnic and collateral microcirculation has b...

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Detalles Bibliográficos
Autores principales: Li, Tzu-Hao, Huang, Chia-Chang, Yang, Ying-Ying, Lee, Kuei-Chuan, Hsieh, Shie-Liang, Hsieh, Yun-Cheng, Alan, Lin, Lin, Han-Chieh, Lee, Shou-Dong, Tsai, Chang-Youh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731147/
https://www.ncbi.nlm.nih.gov/pubmed/26820153
http://dx.doi.org/10.1371/journal.pone.0147212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731147/
https://www.ncbi.nlm.nih.gov/pubmed/26820153
http://dx.doi.org/10.1371/journal.pone.0147212

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