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Thalidomide Improves the Intestinal Mucosal Injury and Suppresses Mesenteric Angiogenesis and Vasodilatation by Down-Regulating Inflammasomes-Related Cascades in Cirrhotic Rats
BACKGROUND AND AIMS: By blocking TNFα-related effects, thalidomide not only inhibits hepatic fibrogenesis but improves peripheral vasodilatation and portal hypertension in cirrhotic rats. Nonetheless, the investigation of thalidomide's effects on splanchnic and collateral microcirculation has b...
Autores principales: | Li, Tzu-Hao, Huang, Chia-Chang, Yang, Ying-Ying, Lee, Kuei-Chuan, Hsieh, Shie-Liang, Hsieh, Yun-Cheng, Alan, Lin, Lin, Han-Chieh, Lee, Shou-Dong, Tsai, Chang-Youh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731147/ https://www.ncbi.nlm.nih.gov/pubmed/26820153 http://dx.doi.org/10.1371/journal.pone.0147212 |
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