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Nuclear Hormone Receptor LXRα Inhibits Adipocyte Differentiation of Mesenchymal Stem Cells with Wnt/beta-catenin Signaling
Nuclear hormone receptor liver X receptor-alpha (LXRα) plays a vital role in cholesterol homeostasis and is reported to play a role in adipose function and obesity although this is controversial. Conversely, mesenchymal stem cells (MSCs) are suggested to be a major source of adipocyte generation. Ac...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731266/ https://www.ncbi.nlm.nih.gov/pubmed/26595172 http://dx.doi.org/10.1038/labinvest.2015.141 |