Cargando…

Nuclear Hormone Receptor LXRα Inhibits Adipocyte Differentiation of Mesenchymal Stem Cells with Wnt/beta-catenin Signaling

Nuclear hormone receptor liver X receptor-alpha (LXRα) plays a vital role in cholesterol homeostasis and is reported to play a role in adipose function and obesity although this is controversial. Conversely, mesenchymal stem cells (MSCs) are suggested to be a major source of adipocyte generation. Ac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsushita, Kenichi, Morello, Fulvio, Zhang, Zhiping, Masuda, Tomoko, Iwanaga, Shiro, Steffensen, Knut R., Gustafsson, Jan-Åke, Pratt, Richard E., Dzau, Victor J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731266/ https://www.ncbi.nlm.nih.gov/pubmed/26595172 http://dx.doi.org/10.1038/labinvest.2015.141

Ejemplares similares

Deletion of Angiotensin II Type 2 Receptor Accelerates Adipogenesis in Murine Mesenchymal Stem Cells via Wnt10b/beta-catenin Signaling
por: Matsushita, Kenichi, et al.
Publicado: (2016)

Susceptibility of Pancreatic Beta Cells to Fatty Acids Is Regulated by LXR/PPARα-Dependent Stearoyl-Coenzyme A Desaturase
por: Hellemans, Karine H., et al.
Publicado: (2009)

LXRα Promotes the Differentiation of Human Gastric Cancer Cells through Inactivation of Wnt/β-catenin Signaling
por: Gao, Yu, et al.
Publicado: (2019)

Glucagon Like Peptide-1 Promotes Adipocyte Differentiation via the Wnt4 Mediated Sequestering of Beta-Catenin
por: Liu, Rui, et al.
Publicado: (2016)

Sexual Dimorphism in Circadian Physiology Is Altered in LXRα Deficient Mice
por: Feillet, Céline, et al.
Publicado: (2016)

Loss of ERβ in Aging LXRαβ Knockout Mice Leads to Colitis
por: Song, Xiaoyu, et al.
Publicado: (2023)

CFTR and Wnt/beta-catenin signaling in lung development
por: Cohen, J Craig, et al.
Publicado: (2008)

Wnt/beta-Catenin Signaling and Small Molecule Inhibitors
por: Voronkov, Andrey, et al.
Publicado: (2012)

Phosphorylation-Dependent Regulation of WNT/Beta-Catenin Signaling
por: Shah, Kinjal, et al.
Publicado: (2022)

MENA Is a Transcriptional Target of the Wnt/Beta-Catenin Pathway
por: Najafov, Ayaz, et al.
Publicado: (2012)

Wnt/beta-catenin pathway: modulating anticancer immune response
por: Pai, Sachin Gopalkrishna, et al.
Publicado: (2017)

The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms
por: Pourcet, Benoit, et al.
Publicado: (2016)

Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis
por: Feng, Ke, et al.
Publicado: (2021)

Activation of WNT/Beta‐Catenin Signaling and Regulation of the Farnesoid X Receptor/Beta‐Catenin Complex After Murine Bile Duct Ligation
por: Zhang, Rong, et al.
Publicado: (2019)

LXR Suppresses Inflammatory Gene Expression and Neutrophil Migration through cis-Repression and Cholesterol Efflux
por: Thomas, David G., et al.
Publicado: (2018)

Hexane Extract of Chloranthus japonicus Increases Adipocyte Differentiation by Acting on Wnt/β-Catenin Signaling Pathway
por: Yun, Ui Jeong, et al.
Publicado: (2021)

LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of Gnathostomes
por: Fonseca, Elza, et al.
Publicado: (2017)

Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease
por: Becares, Natalia, et al.
Publicado: (2019)

Second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathway
por: Perez-Plasencia, Carlos, et al.
Publicado: (2008)

Wnt/beta-catenin signaling in embryonic stem cell converted tumor cells
por: Peng, Xinrong, et al.
Publicado: (2012)

Aberrant Wnt/Beta-Catenin Pathway Activation in Dialysate-Induced Peritoneal Fibrosis
por: Guo, Yuanyuan, et al.
Publicado: (2017)

The Emerging Roles of Cancer Stem Cells and Wnt/Beta-Catenin Signaling in Hepatoblastoma
por: Mavila, Nirmala, et al.
Publicado: (2019)

ODP354 Telomeres Length and Wnt/beta-catenin Pathway in Adamantinomatous Craniopharyngiomas
por: Ítalo S. Mota, José, et al.
Publicado: (2022)

The small molecule indirubin-3′-oxime activates Wnt/β-catenin signaling and inhibits adipocyte differentiation and obesity
por: Choi, O M, et al.
Publicado: (2014)

Discovery and functional assessment of a novel adipocyte population driven by intracellular Wnt/β-catenin signaling in mammals
por: Liu, Zhi, et al.
Publicado: (2022)

Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGFβ, and Wnt/β-catenin Signaling in Adrenocortical Carcinoma Cells
por: Ehrlund, Anna, et al.
Publicado: (2012)

Tumor Suppressor Gene XEDAR Promotes Differentiation and Suppresses Proliferation and Migration of Gastric Cancer Cells Through Upregulating the RELA/LXRα Axis and Deactivating the Wnt/β-Catenin Pathway
por: Zhang, Xinwu, et al.
Publicado: (2021)

Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches
por: Chen, Meimei, et al.
Publicado: (2018)

Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinoma
por: Ji, Junfang, et al.
Publicado: (2011)

Thermodynamics in Gliomas: Interactions between the Canonical WNT/Beta-Catenin Pathway and PPAR Gamma
por: Vallée, Alexandre, et al.
Publicado: (2017)

Wnt-β-Catenin Signaling Promotes the Maturation of Mast Cells
por: Yamaguchi, Tomoko, et al.
Publicado: (2016)

Ginsenoside Rb1 Facilitates Browning by Repressing Wnt/β-Catenin Signaling in 3T3-L1 Adipocytes
por: Fan, Qingxin, et al.
Publicado: (2021)

Adipocyte-derived CCDC3 promotes tumorigenesis in epithelial ovarian cancer through the Wnt/ß-catenin signalling pathway
por: Wang, Fen, et al.
Publicado: (2023)

miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages
por: Vinod, Manjula, et al.
Publicado: (2014)

Molecular hydrogen suppresses activated Wnt/β-catenin signaling
por: Lin, Yingni, et al.
Publicado: (2016)

LXRα improves myocardial glucose tolerance and reduces cardiac hypertrophy in a mouse model of obesity-induced type 2 diabetes
por: Cannon, Megan V., et al.
Publicado: (2015)

Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans
por: Minniti, Mirko E., et al.
Publicado: (2020)

Ectopic Wnt/Beta–Catenin Signaling Induces Neurogenesis in the Spinal Cord and Hindbrain Floor Plate
por: Joksimovic, Milan, et al.
Publicado: (2012)

Organized Emergence of Multiple-Generations of Teeth in Snakes Is Dysregulated by Activation of Wnt/Beta-Catenin Signalling
por: Gaete, Marcia, et al.
Publicado: (2013)

Recurrent Chromosome 22 Deletions in Osteoblastoma Affect Inhibitors of the Wnt/Beta-Catenin Signaling Pathway
por: Nord, Karolin H., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_jobcflc3sk9o761jhc3f44blji