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The evolving roles of canonical WNT signaling in stem cells and tumorigenesis: Implications in targeted cancer therapies

The canonical WNT/β-catenin signaling pathway governs a myriad of biological processes underlying development and maintenance of adult tissue homeostasis, including regulation of stem cell self-renewal, cell proliferation, differentiation, and apoptosis. WNTs are secreted lipid-modified glycoprotein...

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Detalles Bibliográficos
Autores principales: Yang, Ke, Wang, Xin, Zhang, Hongmei, Wang, Zhongliang, Nan, Guoxin, Li, Yasha, Zhang, Fugui, Mohammed, Maryam K., Haydon, Rex C., Luu, Hue H., Bi, Yang, He, Tong-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731283/
https://www.ncbi.nlm.nih.gov/pubmed/26618721
http://dx.doi.org/10.1038/labinvest.2015.144