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Neurexin 1 (NRXN1) Splice Isoform Expression During Human Neocortical Development and Aging

Neurexin 1 (NRXN1), a presynaptic adhesion molecule, is implicated in several neurodevelopmental disorders characterized by synaptic dysfunction including, autism, intellectual disability, and schizophrenia. To gain insight into NRXN1’s involvement in human cortical development we used quantitative...

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Detalles Bibliográficos
Autores principales: Jenkins, Aaron K., Paterson, Clare, Wang, Yanhong, Hyde, Thomas M., Kleinman, Joel E., Law, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731316/
https://www.ncbi.nlm.nih.gov/pubmed/26216298
http://dx.doi.org/10.1038/mp.2015.107