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A Study of Alterations in DNA Epigenetic Modifications (5mC and 5hmC) and Gene Expression Influenced by Simulated Microgravity in Human Lymphoblastoid Cells

Cells alter their gene expression in response to exposure to various environmental changes. Epigenetic mechanisms such as DNA methylation are believed to regulate the alterations in gene expression patterns. In vitro and in vivo studies have documented changes in cellular proliferation, cytoskeletal...

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Detalles Bibliográficos
Autores principales: Chowdhury, Basudev, Seetharam, Arun, Wang, Zhiping, Liu, Yunlong, Lossie, Amy C., Thimmapuram, Jyothi, Irudayaraj, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731572/
https://www.ncbi.nlm.nih.gov/pubmed/26820575
http://dx.doi.org/10.1371/journal.pone.0147514