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A Study of Alterations in DNA Epigenetic Modifications (5mC and 5hmC) and Gene Expression Influenced by Simulated Microgravity in Human Lymphoblastoid Cells
Cells alter their gene expression in response to exposure to various environmental changes. Epigenetic mechanisms such as DNA methylation are believed to regulate the alterations in gene expression patterns. In vitro and in vivo studies have documented changes in cellular proliferation, cytoskeletal...
Autores principales: | Chowdhury, Basudev, Seetharam, Arun, Wang, Zhiping, Liu, Yunlong, Lossie, Amy C., Thimmapuram, Jyothi, Irudayaraj, Joseph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731572/ https://www.ncbi.nlm.nih.gov/pubmed/26820575 http://dx.doi.org/10.1371/journal.pone.0147514 |
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