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The Relative Contribution of NMDARs to Excitatory Postsynaptic Currents is Controlled by Ca(2+)-Induced Inactivation

NMDA receptors (NMDARs) are important mediators of excitatory synaptic transmission and plasticity. A hallmark of these channels is their high permeability to Ca(2+). At the same time, they are themselves inhibited by the elevation of intracellular Ca(2+) concentration. It is unclear however, whethe...

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Detalles Bibliográficos
Autores principales: Valiullina, Fliza, Zakharova, Yulia, Mukhtarov, Marat, Draguhn, Andreas, Burnashev, Nail, Rozov, Andrei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731592/
https://www.ncbi.nlm.nih.gov/pubmed/26858606
http://dx.doi.org/10.3389/fncel.2016.00012