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A human beta cell line with drug inducible excision of immortalizing transgenes

OBJECTIVES: Access to immortalized human pancreatic beta cell lines that are phenotypically close to genuine adult beta cells, represent a major tool to better understand human beta cell physiology and develop new therapeutics for Diabetes. Here we derived a new conditionally immortalized human beta...

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Detalles Bibliográficos
Autores principales: Benazra, Marion, Lecomte, Marie-José, Colace, Claire, Müller, Andreas, Machado, Cécile, Pechberty, Severine, Bricout-Neveu, Emilie, Grenier-Godard, Maud, Solimena, Michele, Scharfmann, Raphaël, Czernichow, Paul, Ravassard, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731729/
https://www.ncbi.nlm.nih.gov/pubmed/26909308
http://dx.doi.org/10.1016/j.molmet.2015.09.008