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Matrix metalloproteinase 12 modulates high-fat-diet induced glomerular fibrogenesis and inflammation in a mouse model of obesity

Obesity-induced kidney injury contributes to albuminuria, which is characterized by a progressive decline in renal function leading to glomerulosclerosis and renal fibrosis. Matrix metalloproteinases (MMPs) modulate inflammation and fibrosis by degrading a variety of extracellular matrix and regulat...

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Detalles Bibliográficos
Autores principales: Niu, Honglin, Li, Ying, Li, Haibin, Chi, Yanqing, Zhuang, Minghui, Zhang, Tao, Liu, Maodong, Nie, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731752/
https://www.ncbi.nlm.nih.gov/pubmed/26822129
http://dx.doi.org/10.1038/srep20171