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Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells

Valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) are both HDAC inhibitors (HDACi). Previous studies indicated that both inhibitors show therapeutic effects on acute myeloid leukaemia (AML), while the differential impacts of the two different HDACi on AML treatment still remains elusive...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaoyu, Liu, Xin, Cheng, Zhongyi, Zhu, Jun, Xu, Lei, Wang, Fengsong, Qi, Wulin, Yan, Jiawei, Liu, Ning, Sun, Zimin, Liu, Huilan, Peng, Xiaojun, Hao, Yingchan, Zheng, Nan, Wu, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731804/
https://www.ncbi.nlm.nih.gov/pubmed/26822725
http://dx.doi.org/10.1038/srep19926