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Group A Streptococcus exploits human plasminogen for bacterial translocation across epithelial barrier via tricellular tight junctions

Group A Streptococcus (GAS) is a human-specific pathogen responsible for local suppurative and life-threatening invasive systemic diseases. Interaction of GAS with human plasminogen (PLG) is a salient characteristic for promoting their systemic dissemination. In the present study, a serotype M28 str...

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Detalles Bibliográficos
Autores principales: Sumitomo, Tomoko, Nakata, Masanobu, Higashino, Miharu, Yamaguchi, Masaya, Kawabata, Shigetada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731814/
https://www.ncbi.nlm.nih.gov/pubmed/26822058
http://dx.doi.org/10.1038/srep20069