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A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis

The main etiopathogenesis of rheumatoid arthritis (RA) is overexpressed inflammatory cytokines and tissue injury mediated by persistent NF-κB activation. MicroRNAs widely participate in the regulation of target gene expression and play important roles in various diseases. Here, we explored the mecha...

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Detalles Bibliográficos
Autores principales: Mu, Nan, Gu, Jintao, Huang, Tonglie, Zhang, Cun, Shu, Zhen, Li, Meng, Hao, Qiang, Li, Weina, Zhang, Wangqian, Zhao, Jinkang, Zhang, Yong, Huang, Luyu, Wang, Shuning, Jin, Xiaohang, Xue, Xiaochang, Zhang, Wei, Zhang, Yingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731824/
https://www.ncbi.nlm.nih.gov/pubmed/26821827
http://dx.doi.org/10.1038/srep20059