A Turnstile Mechanism for the Controlled Growth of Biosynthetic Intermediates on Assembly Line Polyketide Synthases

[Image: see text] Vectorial polyketide biosynthesis on an assembly line polyketide synthase is the most distinctive property of this family of biological machines, while providing the key conceptual tool for the bioinformatic decoding of new antibiotic pathways. We now show that the action of the en...

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Detalles Bibliográficos
Autores principales: Lowry, Brian, Li, Xiuyuan, Robbins, Thomas, Cane, David E., Khosla, Chaitan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2016
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731828/
https://www.ncbi.nlm.nih.gov/pubmed/26878060
http://dx.doi.org/10.1021/acscentsci.5b00321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731828/
https://www.ncbi.nlm.nih.gov/pubmed/26878060
http://dx.doi.org/10.1021/acscentsci.5b00321

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