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MicroRNA-224 sustains Wnt/β-catenin signaling and promotes aggressive phenotype of colorectal cancer

BACKGROUND: Growing evidence suggests that Wnt/β-catenin pathway plays an important role in CRC development, progression and metastasis. Aberrant miR-224 expression has been reported in CRC. However, the mechanism of miR-224 promotes both proliferation and metastatic ability largely remains unclear....

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Detalles Bibliográficos
Autores principales: Li, Tingting, Lai, Qiuhua, Wang, Shuyang, Cai, Juanjuan, Xiao, Zhiyuan, Deng, Danling, He, Liuqing, Jiao, Hongli, Ye, Yaping, Liang, Li, Ding, Yanqing, Liao, Wenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731927/
https://www.ncbi.nlm.nih.gov/pubmed/26822534
http://dx.doi.org/10.1186/s13046-016-0287-1