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Long non-coding RNAs display higher natural expression variation than protein-coding genes in healthy humans

BACKGROUND: Long non-coding RNAs (lncRNAs) are increasingly implicated as gene regulators and may ultimately be more numerous than protein-coding genes in the human genome. Despite large numbers of reported lncRNAs, reference annotations are likely incomplete due to their lower and tighter tissue-sp...

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Detalles Bibliográficos
Autores principales: Kornienko, Aleksandra E., Dotter, Christoph P., Guenzl, Philipp M., Gisslinger, Heinz, Gisslinger, Bettina, Cleary, Ciara, Kralovics, Robert, Pauler, Florian M., Barlow, Denise P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731934/
https://www.ncbi.nlm.nih.gov/pubmed/26821746
http://dx.doi.org/10.1186/s13059-016-0873-8