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Comparative genome-wide analysis and evolutionary history of haemoglobin-processing and haem detoxification enzymes in malarial parasites

BACKGROUND: Malaria parasites have evolved a series of intricate mechanisms to survive and propagate within host red blood cells. Intra-erythrocytic parasitism requires these organisms to digest haemoglobin and detoxify iron-bound haem. These tasks are executed by haemoglobin-specific proteases and...

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Detalles Bibliográficos
Autores principales: Ponsuwanna, Patrath, Kochakarn, Theerarat, Bunditvorapoom, Duangkamon, Kümpornsin, Krittikorn, Otto, Thomas D., Ridenour, Chase, Chotivanich, Kesinee, Wilairat, Prapon, White, Nicholas J., Miotto, Olivo, Chookajorn, Thanat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731938/
https://www.ncbi.nlm.nih.gov/pubmed/26821618
http://dx.doi.org/10.1186/s12936-016-1097-9