Prioritization of anti-malarial hits from nature: chemo-informatic profiling of natural products with in vitro antiplasmodial activities and currently registered anti-malarial drugs

BACKGROUND: A large number of natural products have shown in vitro antiplasmodial activities. Early identification and prioritization of these natural products with potential for novel mechanism of action, desirable pharmacokinetics and likelihood for development into drugs is advantageous. Chemo-in...

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Detalles Bibliográficos
Autores principales: Egieyeh, Samuel Ayodele, Syce, James, Malan, Sarel F., Christoffels, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731946/
https://www.ncbi.nlm.nih.gov/pubmed/26823078
http://dx.doi.org/10.1186/s12936-016-1087-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731946/
https://www.ncbi.nlm.nih.gov/pubmed/26823078
http://dx.doi.org/10.1186/s12936-016-1087-y

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