High yield 1,3-propanediol production by rational engineering of the 3-hydroxypropionaldehyde bottleneck in Citrobacter werkmanii

BACKGROUND: Imbalance in cofactors causing the accumulation of intermediates in biosynthesis pathways is a frequently occurring problem in metabolic engineering when optimizing a production pathway in a microorganism. In our previous study, a single knock-out Citrobacter werkmanii ∆dhaD was construc...

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Detalles Bibliográficos
Autores principales: Maervoet, Veerle E. T., De Maeseneire, Sofie L., Avci, Fatma G., Beauprez, Joeri, Soetaert, Wim K., De Mey, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731958/
https://www.ncbi.nlm.nih.gov/pubmed/26822953
http://dx.doi.org/10.1186/s12934-016-0421-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731958/
https://www.ncbi.nlm.nih.gov/pubmed/26822953
http://dx.doi.org/10.1186/s12934-016-0421-y

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