An integrative genome-wide transcriptome reveals that candesartan is neuroprotective and a candidate therapeutic for Alzheimer’s disease

BACKGROUND: Alzheimer’s disease is the most frequent age-related dementia, and is currently without treatment. To identify possible targets for early therapeutic intervention we focused on glutamate excitotoxicity, a major early pathogenic factor, and the effects of candesartan, an angiotensin recep...

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Detalles Bibliográficos
Autores principales: Elkahloun, Abdel G., Hafko, Roman, Saavedra, Juan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731966/
https://www.ncbi.nlm.nih.gov/pubmed/26822027
http://dx.doi.org/10.1186/s13195-015-0167-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731966/
https://www.ncbi.nlm.nih.gov/pubmed/26822027
http://dx.doi.org/10.1186/s13195-015-0167-5

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