HIV protease inhibitors disrupt astrocytic glutamate transporter function and neurobehavioral performance

OBJECTIVE: The neurotoxic actions of the HIV protease inhibitors, amprenavir (APV) and lopinavir (LPV) were investigated. DESIGN: With combination antiretroviral therapy (cART), HIV-infected persons exhibit neurocognitive impairments, raising the possibility that cART might exert adverse central ner...

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Detalles Bibliográficos
Autores principales: Vivithanaporn, Pornpun, Asahchop, Eugene L., Acharjee, Shaona, Baker, Glen B., Power, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732003/
https://www.ncbi.nlm.nih.gov/pubmed/26558720
http://dx.doi.org/10.1097/QAD.0000000000000955

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732003/
https://www.ncbi.nlm.nih.gov/pubmed/26558720
http://dx.doi.org/10.1097/QAD.0000000000000955

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