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Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes
It has been reported that reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, take part in osteoclast differentiation as intra-cellular signaling molecules. The current assumed signaling cascade from RANK to ROS production is RANK, TRAF6, Rac1, and then Nox. The target molecules...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732015/ https://www.ncbi.nlm.nih.gov/pubmed/26795736 http://dx.doi.org/10.1016/j.redox.2016.01.006 |