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Molecular regulatory mechanisms of osteoclastogenesis through cytoprotective enzymes

It has been reported that reactive oxygen species (ROS), such as hydrogen peroxide and superoxide, take part in osteoclast differentiation as intra-cellular signaling molecules. The current assumed signaling cascade from RANK to ROS production is RANK, TRAF6, Rac1, and then Nox. The target molecules...

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Detalles Bibliográficos
Autores principales: Kanzaki, Hiroyuki, Shinohara, Fumiaki, Kanako, Itohiya, Yamaguchi, Yuuki, Fukaya, Sari, Miyamoto, Yutaka, Wada, Satoshi, Nakamura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732015/
https://www.ncbi.nlm.nih.gov/pubmed/26795736
http://dx.doi.org/10.1016/j.redox.2016.01.006