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Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair

An H(+)-ion sensor based on a gated lateral bipolar junction transistor (BJT) pair that can operate without the classical reference electrode is proposed. The device is a special type of ion-sensitive field-effect transistor (ISFET). Classical ISFETs have the advantage of miniaturization, but  they...

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Autores principales: Yuan, Heng, Zhang, Jixing, Cao, Chuangui, Zhang, Gangyuan, Zhang, Shaoda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732047/
https://www.ncbi.nlm.nih.gov/pubmed/26703625
http://dx.doi.org/10.3390/s16010014
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author Yuan, Heng
Zhang, Jixing
Cao, Chuangui
Zhang, Gangyuan
Zhang, Shaoda
author_facet Yuan, Heng
Zhang, Jixing
Cao, Chuangui
Zhang, Gangyuan
Zhang, Shaoda
author_sort Yuan, Heng
collection PubMed
description An H(+)-ion sensor based on a gated lateral bipolar junction transistor (BJT) pair that can operate without the classical reference electrode is proposed. The device is a special type of ion-sensitive field-effect transistor (ISFET). Classical ISFETs have the advantage of miniaturization, but  they are difficult to fabricate by a single fabrication process because of the bulky and brittle reference electrode materials. Moreover, the reference electrodes need to be separated from the sensor device in some cases. The proposed device is composed of two gated lateral BJT components, one of which had a silicide layer while the other was without the layer. The two components were operated under the metal-oxide semiconductor field-effect transistor (MOSFET)-BJT hybrid mode, which can be controlled by emitter voltage and base current. Buffer solutions with different pH values were used as the sensing targets to verify the characteristics of the proposed device. Owing to their different sensitivities, both components could simultaneously detect the H(+)-ion concentration and function as a reference to each other. Per the experimental results, the sensitivity of the proposed device was found to be approximately 0.175 μA/pH. This experiment demonstrates enormous potential to lower the cost of the ISFET-based sensor technology.
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spelling pubmed-47320472016-02-12 Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair Yuan, Heng Zhang, Jixing Cao, Chuangui Zhang, Gangyuan Zhang, Shaoda Sensors (Basel) Article An H(+)-ion sensor based on a gated lateral bipolar junction transistor (BJT) pair that can operate without the classical reference electrode is proposed. The device is a special type of ion-sensitive field-effect transistor (ISFET). Classical ISFETs have the advantage of miniaturization, but  they are difficult to fabricate by a single fabrication process because of the bulky and brittle reference electrode materials. Moreover, the reference electrodes need to be separated from the sensor device in some cases. The proposed device is composed of two gated lateral BJT components, one of which had a silicide layer while the other was without the layer. The two components were operated under the metal-oxide semiconductor field-effect transistor (MOSFET)-BJT hybrid mode, which can be controlled by emitter voltage and base current. Buffer solutions with different pH values were used as the sensing targets to verify the characteristics of the proposed device. Owing to their different sensitivities, both components could simultaneously detect the H(+)-ion concentration and function as a reference to each other. Per the experimental results, the sensitivity of the proposed device was found to be approximately 0.175 μA/pH. This experiment demonstrates enormous potential to lower the cost of the ISFET-based sensor technology. MDPI 2015-12-23 /pmc/articles/PMC4732047/ /pubmed/26703625 http://dx.doi.org/10.3390/s16010014 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yuan, Heng
Zhang, Jixing
Cao, Chuangui
Zhang, Gangyuan
Zhang, Shaoda
Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title_full Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title_fullStr Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title_full_unstemmed Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title_short Novel H(+)-Ion Sensor Based on a Gated Lateral BJT Pair
title_sort novel h(+)-ion sensor based on a gated lateral bjt pair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732047/
https://www.ncbi.nlm.nih.gov/pubmed/26703625
http://dx.doi.org/10.3390/s16010014
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