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Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1

Sphingolipid (SL) biosynthesis is negatively regulated by the highly conserved endoplasmic reticulum-localized Orm family proteins. Defective SL synthesis in Saccharomyces cerevisiae leads to increased phosphorylation and inhibition of Orm proteins by the kinase Ypk1. Here we present evidence that t...

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Detalles Bibliográficos
Autores principales: Chauhan, Neha, Han, Gongshe, Somashekarappa, Niranjanakumari, Gable, Kenneth, Dunn, Teresa, Kohlwein, Sepp D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732232/
https://www.ncbi.nlm.nih.gov/pubmed/26634277
http://dx.doi.org/10.1074/jbc.M115.693200