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Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons
Defective transport of mitochondria in axons is implicated in the pathogenesis of several age-associated neurodegenerative diseases. However, the regulation and function of axonal mitochondrial motility during normal ageing is poorly understood. Here, we use novel imaging procedures to characterise...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732301/ https://www.ncbi.nlm.nih.gov/pubmed/26598558 http://dx.doi.org/10.1242/jcs.179184 |