CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells

PHD1 (also known as EGLN2) belongs to a family of prolyl hydroxylases (PHDs) that are involved in the control of the cellular response to hypoxia. PHD1 is also able to regulate mitotic progression through the regulation of the crucial centrosomal protein Cep192, establishing a link between the oxyge...

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Detalles Bibliográficos
Autores principales: Ortmann, Brian, Bensaddek, Dalila, Carvalhal, Sara, Moser, Sandra C., Mudie, Sharon, Griffis, Eric R., Swedlow, Jason R., Lamond, Angus I., Rocha, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732302/
https://www.ncbi.nlm.nih.gov/pubmed/26644182
http://dx.doi.org/10.1242/jcs.179911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732302/
https://www.ncbi.nlm.nih.gov/pubmed/26644182
http://dx.doi.org/10.1242/jcs.179911

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