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Anti-inflammatory effects of intravenous methotrexate associated with lipid nanoemulsions on antigen-induced arthritis

OBJECTIVE: To test the hypothesis that intravenous use of methotrexate associated with lipid nanoemulsions can achieve superior anti-inflammatory effects in the joints of rabbits with antigen-induced arthritis compared with commercial methotrexate. METHODS: Arthritis was induced in New Zealand rabbi...

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Detalles Bibliográficos
Autores principales: Mello, Suzana B V, Tavares, Elaine R, Guido, Maria Carolina, Bonfá, Eloisa, Maranhão, Raul C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732406/
https://www.ncbi.nlm.nih.gov/pubmed/26872084
http://dx.doi.org/10.6061/clinics/2016(01)09