Methods for identification and confirmation of targeted subgroups in clinical trials: A systematic review

Important objectives in the development of stratified medicines include the identification and confirmation of subgroups of patients with a beneficial treatment effect and a positive benefit-risk balance. We report the results of a literature review on methodological approaches to the design and ana...

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Detalles Bibliográficos
Autores principales: Ondra, Thomas, Dmitrienko, Alex, Friede, Tim, Graf, Alexandra, Miller, Frank, Stallard, Nigel, Posch, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732423/
https://www.ncbi.nlm.nih.gov/pubmed/26378339
http://dx.doi.org/10.1080/10543406.2015.1092034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732423/
https://www.ncbi.nlm.nih.gov/pubmed/26378339
http://dx.doi.org/10.1080/10543406.2015.1092034

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