Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress

We recently reported on our success to generate deletion mutants of the genes encoding glutamate dehydrogenase (GDH) and glutamine oxoglutarate aminotransferase (GOGAT) in M. bovis BCG, despite their in vitro essentiality in M. tuberculosis. We could use these mutants to delineate the roles of GDH a...

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Detalles Bibliográficos
Autores principales: Gallant, James L., Viljoen, Albertus J., van Helden, Paul D., Wiid, Ian J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732601/
https://www.ncbi.nlm.nih.gov/pubmed/26824899
http://dx.doi.org/10.1371/journal.pone.0147706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732601/
https://www.ncbi.nlm.nih.gov/pubmed/26824899
http://dx.doi.org/10.1371/journal.pone.0147706

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