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Glutamate Dehydrogenase Is Required by Mycobacterium bovis BCG for Resistance to Cellular Stress
We recently reported on our success to generate deletion mutants of the genes encoding glutamate dehydrogenase (GDH) and glutamine oxoglutarate aminotransferase (GOGAT) in M. bovis BCG, despite their in vitro essentiality in M. tuberculosis. We could use these mutants to delineate the roles of GDH a...
Autores principales: | Gallant, James L., Viljoen, Albertus J., van Helden, Paul D., Wiid, Ian J. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732601/ https://www.ncbi.nlm.nih.gov/pubmed/26824899 http://dx.doi.org/10.1371/journal.pone.0147706 |
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