Reduced CYFIP1 in Human Neural Progenitors Results in Dysregulation of Schizophrenia and Epilepsy Gene Networks

Deletions encompassing the BP1-2 region at 15q11.2 increase schizophrenia and epilepsy risk, but only some carriers have either disorder. To investigate the role of CYFIP1, a gene within the region, we performed knockdown experiments in human neural progenitors derived from donors with 2 copies of e...

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Detalles Bibliográficos
Autores principales: Nebel, Rebecca A., Zhao, Dejian, Pedrosa, Erika, Kirschen, Jill, Lachman, Herbert M., Zheng, Deyou, Abrahams, Brett S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732616/
https://www.ncbi.nlm.nih.gov/pubmed/26824476
http://dx.doi.org/10.1371/journal.pone.0148039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732616/
https://www.ncbi.nlm.nih.gov/pubmed/26824476
http://dx.doi.org/10.1371/journal.pone.0148039

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