FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc

Bone-morphogenetic protein-7 (BMP-7) is a growth factor that plays a major role in mediating anabolism and anti-catabolism of the intervertebral disc matrix and cell homeostasis. In osteoblasts, Forkhead box protein C2 (FoxC2) is a downstream target of BMPs and promotes cell proliferation and differ...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Fu, Changfeng, Chen, Yong, Xu, Feng, Wang, Zhenyu, Qu, Zhigang, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732619/
https://www.ncbi.nlm.nih.gov/pubmed/26824865
http://dx.doi.org/10.1371/journal.pone.0147764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732619/
https://www.ncbi.nlm.nih.gov/pubmed/26824865
http://dx.doi.org/10.1371/journal.pone.0147764

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