Cargando…

FoxC2 Enhances BMP7-Mediated Anabolism in Nucleus Pulposus Cells of the Intervertebral Disc

Bone-morphogenetic protein-7 (BMP-7) is a growth factor that plays a major role in mediating anabolism and anti-catabolism of the intervertebral disc matrix and cell homeostasis. In osteoblasts, Forkhead box protein C2 (FoxC2) is a downstream target of BMPs and promotes cell proliferation and differ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Zheng, Fu, Changfeng, Chen, Yong, Xu, Feng, Wang, Zhenyu, Qu, Zhigang, Liu, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732619/ https://www.ncbi.nlm.nih.gov/pubmed/26824865 http://dx.doi.org/10.1371/journal.pone.0147764

Ejemplares similares

Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008)

Proteomic Signature of Nucleus Pulposus in Fetal Intervertebral Disc
por: Rajasekaran, Shanmuganathan, et al.
Publicado: (2020)

BMP7 ameliorates intervertebral disc degeneration in type 1 diabetic rats by inhibiting pyroptosis of nucleus pulposus cells and NLRP3 inflammasome activity
por: Yu, Xiao-Jun, et al.
Publicado: (2023)

Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
por: Sakai, Daisuke, et al.
Publicado: (2012)

Changes in the Molecular Phenotype of Nucleus Pulposus Cells with Intervertebral Disc Aging
por: Tang, Xinyan, et al.
Publicado: (2012)

Characterisation of porous knitted titanium for replacement of intervertebral disc nucleus pulposus
por: Tendulkar, Gauri, et al.
Publicado: (2017)

Circular RNAs in nucleus pulposus cell function and intervertebral disc degeneration
por: Li, Zheng, et al.
Publicado: (2019)

Expression of ANGPTL4 in Nucleus Pulposus Tissues Is Associated with Intervertebral Disc Degeneration
por: Liu, Fan-jie, et al.
Publicado: (2021)

Natural Products of Pharmacology and Mechanisms in Nucleus Pulposus Cells and Intervertebral Disc Degeneration
por: Chen, Hai-Wei, et al.
Publicado: (2021)

Endoscopic removal of nucleus pulposus of intervertebral disc on lumbar intervertebral disc protrusion and the influence on inflammatory factors and immune function
por: Xu, Gang, et al.
Publicado: (2020)

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration
por: Jia, Haoruo, et al.
Publicado: (2022)

Successful fishing for nucleus pulposus progenitor cells of the intervertebral disc across species
por: Sakai, Daisuke, et al.
Publicado: (2018)

Effects of puerarin on the intervertebral disc degeneration and biological characteristics of nucleus pulposus cells
por: Tang, Hengtao, et al.
Publicado: (2022)

GLUT1 is redundant in hypoxic and glycolytic nucleus pulposus cells of the intervertebral disc
por: Johnston, Shira N., et al.
Publicado: (2023)

PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022)

Ex Vivo Observation of Human Nucleus Pulposus Chondrocytes Isolated From Degenerated Intervertebral Discs
por: Wang, Feng, et al.
Publicado: (2011)

Stiffening of the nucleus pulposus upon axial loading of the intervertebral disc: An experimental in situ study
por: Beekmans, Steven V., et al.
Publicado: (2018)

Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs
por: Chen, Chen, et al.
Publicado: (2020)

Discovery and Application of Postnatal Nucleus Pulposus Progenitors Essential for Intervertebral Disc Homeostasis and Degeneration
por: Gao, Bo, et al.
Publicado: (2022)

Comparative metagenomic analysis of human intervertebral disc nucleus pulposus and cartilaginous end plates
por: Shanmuganathan, Rajasekaran, et al.
Publicado: (2022)

Interleukin 1 Polymorphisms Contribute to Intervertebral Disc Degeneration Risk: A Meta-Analysis
por: Wang, Zheng, et al.
Publicado: (2016)

Apigenin Alleviates Intervertebral Disc Degeneration via Restoring Autophagy Flux in Nucleus Pulposus Cells
por: Xie, Chenglong, et al.
Publicado: (2022)

Augmented Chondroitin Sulfate Proteoglycan Has Therapeutic Potential for Intervertebral Disc Degeneration by Stimulating Anabolic Turnover in Bovine Nucleus Pulposus Cells under Changes in Hydrostatic Pressure
por: Takeoka, Yoshiki, et al.
Publicado: (2021)

Acacetin Alleviates Inflammation and Matrix Degradation in Nucleus Pulposus Cells and Ameliorates Intervertebral Disc Degeneration in vivo
por: Wang, Hao, et al.
Publicado: (2020)

Shh Signaling from the Nucleus Pulposus Is Required for the Postnatal Growth and Differentiation of the Mouse Intervertebral Disc
por: Dahia, Chitra Lekha, et al.
Publicado: (2012)

The cytokine and chemokine expression profile of nucleus pulposus cells: implications for degeneration and regeneration of the intervertebral disc
por: Phillips, Kate L E, et al.
Publicado: (2013)

Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration
por: Arkesteijn, Irene TM, et al.
Publicado: (2015)

Regenerative and Immunogenic Characteristics of Cultured Nucleus Pulposus Cells from Human Cervical Intervertebral Discs
por: Stich, Stefan, et al.
Publicado: (2015)

Effect of Static Load on the Nucleus Pulposus of Rabbit Intervertebral Disc Motion Segment in an Organ Culture
por: Zhan, Jia-Wen, et al.
Publicado: (2016)

Effect of optimized collagenase digestion on isolated and cultured nucleus pulposus cells in degenerated intervertebral discs
por: Feng, Xu, et al.
Publicado: (2018)

Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells
por: Mohanty, Sarthak, et al.
Publicado: (2019)

The Upregulation of COX2 in Human Degenerated Nucleus Pulposus: The Association of Inflammation with Intervertebral Disc Degeneration
por: Liu, Chang, et al.
Publicado: (2021)

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration
por: Zhang, Guang‐Zhi, et al.
Publicado: (2021)

TMT-Based Proteomics Analysis of Senescent Nucleus Pulposus from Patients with Intervertebral Disc Degeneration
por: Zhang, Guangzhi, et al.
Publicado: (2023)

ERBB2-PTGS2 axis promotes intervertebral disc degeneration by regulating senescence of nucleus pulposus cells
por: Li, Zhao-Cheng., et al.
Publicado: (2023)

Upregulated lnc-HRK-2:1 prompts nucleus pulposus cell senescence in intervertebral disc degeneration
por: Liang, Dongbo, et al.
Publicado: (2020)

Transplantation of allogenic nucleus pulposus cells attenuates intervertebral disc degeneration by inhibiting apoptosis and increasing migration
por: Wang, Weiheng, et al.
Publicado: (2018)

Effects of interleukin‐17A in nucleus pulposus cells and its small‐molecule inhibitors for intervertebral disc disease
por: Suyama, Kaori, et al.
Publicado: (2018)

DPSCs Protect Architectural Integrity and Alleviate Intervertebral Disc Degeneration by Regulating Nucleus Pulposus Immune Status
por: Dong, Xiwen, et al.
Publicado: (2022)

miR-222 induces apoptosis in human intervertebral disc nucleus pulposus cells by targeting Bcl-2
por: Wang, Wei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_scrgqjm3kcso7j2ilitqro3pou