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In Vivo Transplantation of Enteric Neural Crest Cells into Mouse Gut; Engraftment, Functional Integration and Long-Term Safety

OBJECTIVES: Enteric neuropathies are severe gastrointestinal disorders with unsatisfactory outcomes. We aimed to investigate the potential of enteric neural stem cell therapy approaches for such disorders by transplanting mouse enteric neural crest cells (ENCCs) into ganglionic and aganglionic mouse...

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Detalles Bibliográficos
Autores principales: Cooper, Julie E., McCann, Conor J., Natarajan, Dipa, Choudhury, Shanas, Boesmans, Werend, Delalande, Jean-Marie, Vanden Berghe, Pieter, Burns, Alan J., Thapar, Nikhil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732685/
https://www.ncbi.nlm.nih.gov/pubmed/26824433
http://dx.doi.org/10.1371/journal.pone.0147989