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Intravenous high mobility group box 1 upregulates the expression of HIF-1α in the myocardium via a protein kinase B-dependent pathway in rats following acute myocardial ischemia

The effects of intravenous high mobility group box 1 (HMGB1) on myocardial ischemia/reperfusion (I/R) injury remains to be elucidated. The purpose of the present study was to investigate the effects of intravenous HMGB1 on the expression of hypoxia inducible factor-1α (HIF-1α) in the myocardium of r...

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Detalles Bibliográficos
Autores principales: YAO, HENG-CHEN, ZHOU, MIN, ZHOU, YAN-HONG, WANG, LAN-HUA, ZHANG, DE-YONG, HAN, QIAN-FENG, LIU, TAO, WU, LEI, TIAN, KE-LI, ZHANG, MEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732844/
https://www.ncbi.nlm.nih.gov/pubmed/26648172
http://dx.doi.org/10.3892/mmr.2015.4648