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AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease

Angiotensin II, which is the main effector of the renin-angiotensin system, has an important role in intestinal inflammation via the angiotensin II type 1 receptor (AT1R). The present study aimed to investigate the protective effects of the AT1R blocker losartan on 2,4,6-trinitrobenzenesulphonic aci...

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Detalles Bibliográficos
Autores principales: LIU, TIAN-JING, SHI, YONG-YAN, WANG, EN-BO, ZHU, TONG, ZHAO, QUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732858/
https://www.ncbi.nlm.nih.gov/pubmed/26676112
http://dx.doi.org/10.3892/mmr.2015.4686