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AT1R blocker losartan attenuates intestinal epithelial cell apoptosis in a mouse model of Crohn's disease
Angiotensin II, which is the main effector of the renin-angiotensin system, has an important role in intestinal inflammation via the angiotensin II type 1 receptor (AT1R). The present study aimed to investigate the protective effects of the AT1R blocker losartan on 2,4,6-trinitrobenzenesulphonic aci...
Autores principales: | LIU, TIAN-JING, SHI, YONG-YAN, WANG, EN-BO, ZHU, TONG, ZHAO, QUN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732858/ https://www.ncbi.nlm.nih.gov/pubmed/26676112 http://dx.doi.org/10.3892/mmr.2015.4686 |
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