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ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology. Recent work has revealed tissue-specific roles for ILCs; however, the question of how a small population has large effects on immune homeostasis remains unclear. We identify two mechanisms that...

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Detalles Bibliográficos
Autores principales: Pearson, Claire, Thornton, Emily E, McKenzie, Brent, Schaupp, Anna-Lena, Huskens, Nicky, Griseri, Thibault, West, Nathaniel, Tung, Sim, Seddon, Benedict P, Uhlig, Holm H, Powrie, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733039/
https://www.ncbi.nlm.nih.gov/pubmed/26780670
http://dx.doi.org/10.7554/eLife.10066