Cargando…

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

Innate lymphoid cells (ILCs) contribute to host defence and tissue repair but can induce immunopathology. Recent work has revealed tissue-specific roles for ILCs; however, the question of how a small population has large effects on immune homeostasis remains unclear. We identify two mechanisms that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pearson, Claire, Thornton, Emily E, McKenzie, Brent, Schaupp, Anna-Lena, Huskens, Nicky, Griseri, Thibault, West, Nathaniel, Tung, Sim, Seddon, Benedict P, Uhlig, Holm H, Powrie, Fiona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733039/ https://www.ncbi.nlm.nih.gov/pubmed/26780670 http://dx.doi.org/10.7554/eLife.10066

Ejemplares similares

GM-CSF: Orchestrating the Pulmonary Response to Infection
por: McCormick, Thomas S., et al.
Publicado: (2022)

Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation
por: Griseri, Thibault, et al.
Publicado: (2012)

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis
por: Regan-Komito, Daniel, et al.
Publicado: (2020)

Increased GM‐CSF‐producing NCR(‐) ILC3s and neutrophils in the intestinal mucosa exacerbate inflammatory bowel disease
por: Chang, Yuna, et al.
Publicado: (2021)

Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis
por: Griseri, Thibault, et al.
Publicado: (2015)

GM-CSF primes cardiac inflammation in a mouse model of Kawasaki disease
por: Stock, Angus T., et al.
Publicado: (2016)

GM-CSF in inflammation
por: Hamilton, John A.
Publicado: (2019)

OX40 is required for regulatory T cell–mediated control of colitis
por: Griseri, Thibault, et al.
Publicado: (2010)

G-CSF and GM-CSF in clinical trials.
por: Antman, K. H.
Publicado: (1990)

ILC2 Orchestration of Local Immune Function in Adipose Tissue
por: Bénézech, Cécile, et al.
Publicado: (2019)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
por: Lazarus, Hillard M., et al.
Publicado: (2023)

GM-CSF and IL-33 Orchestrate Polynucleation and Polyploidy of Resident Murine Alveolar Macrophages in a Murine Model of Allergic Asthma
por: Quell, Katharina M., et al.
Publicado: (2020)

Unique transcriptome signatures and GM-CSF expression in lymphocytes from patients with spondyloarthritis
por: Al-Mossawi, M. H., et al.
Publicado: (2017)

A role for G-CSF and GM-CSF in nonmyeloid cancers
por: Aliper, Alexander M, et al.
Publicado: (2014)

GM-CSF-Dependent Inflammatory Pathways
por: Hamilton, John A.
Publicado: (2019)

Development of Dendritic Cells from GM-CSF(-/-) Mice in vitro : GM-CSF Enhances Production and Survival of Cells
por: Ni, Keping, et al.
Publicado: (2001)

IL-4-producing ILC2s are required for the differentiation of T(H)2 cells following Heligmosomoides polygyrus infection
por: Pelly, VS, et al.
Publicado: (2016)

Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF(+) T Lymphocytes
por: Bystrom, Jonas, et al.
Publicado: (2017)

Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity
por: Pykhtina, Mariya, et al.
Publicado: (2021)

G-CSF mobilised granulocyte transfusions in 32 paediatric patients with neutropenic sepsis
por: Grigull, Lorenz, et al.
Publicado: (2006)

Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
por: Shiomi, Aoi, et al.
Publicado: (2015)

A Review of GM-CSF Therapy in Sepsis
por: Mathias, Brittany, et al.
Publicado: (2015)

The efficacy and safety of targeting GM-CSF in arthritis
por: Bykerk, Vivian P
Publicado: (2020)

Role of GM-CSF in lung balance and disease
por: Chen, Yingzi, et al.
Publicado: (2023)

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
por: Bosteels, Cedric, et al.
Publicado: (2022)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
por: He, Kai, et al.
Publicado: (2022)

To mobilise or not to mobilise: is that the right question?
por: Hodgson, Carol L., et al.
Publicado: (2023)

G-CSF and GM-CSF Modify Neutrophil Functions at Concentrations found in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2019)

Functional characterization of GM-CSF induced monocyte subsets
por: Däbritz, J, et al.
Publicado: (2008)

Delivery of GM-CSF to Protect against Influenza Pneumonia
por: Subramaniam, Renuka, et al.
Publicado: (2015)

GM-CSF as a therapeutic target in autoimmune diseases
por: Shiomi, Aoi, et al.
Publicado: (2016)

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update
por: Lotfi, Noushin, et al.
Publicado: (2019)

GM-CSF: A Promising Target in Inflammation and Autoimmunity
por: Lee, Kevin M C, et al.
Publicado: (2020)

Localised learning: mobilising belonging among mature-aged students in low socio-economic status regional and remote areas
por: Crawford, Nicole, et al.
Publicado: (2022)

GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?
por: Mishra, Abhishek, et al.
Publicado: (2020)

Prior chemotherapy does not prevent effective mobilisation by G-CSF of peripheral blood progenitor cells.
por: DeLuca, E., et al.
Publicado: (1992)

Glutamine Deprivation Promotes the Generation and Mobilization of MDSCs by Enhancing Expression of G-CSF and GM-CSF
por: Sun, Hong-Wei, et al.
Publicado: (2021)

IL-33 promotes anemia during chronic inflammation by inhibiting differentiation of erythroid progenitors
por: Swann, James W., et al.
Publicado: (2020)

14-3-3 and enolase abundances in the CSF of Prion diseased rats
por: Gushue, Danielle, et al.
Publicado: (2018)

IL-7–dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes
por: Yang, Jie, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_28aef08eqr61pi74t1ectpiuc5